Called to shape what is entrusted to us. God's garden -- Using tools -- Body and soul -- Three helpful cautions, but inadequate guides for shaping human nature. Cure versus enhancement -- Welcoming versus making -- The present versus the future -- Four standards for shaping human nature. Safe -- Genuine improvement -- Increase choice for the recipient -- Best use of always finite resources -- Who applies these standards? The devastating history of coercion, racism, and eugenics -- Checks and balances.