LEADER 00000cam  22000004a 4500 
001    ocn317249552 
003    OCoLC 
005    20130719142726.0 
008    090323t20092009nyua     b    001 0 eng   
010      2009012407 
016 7  101499918|2DNLM 
019    213775632 
020    9781420061680|qhardcover|qalkaline paper 
020    1420061682 
035    (OCoLC)317249552 
035    (OCoLC)317249552 
035    (OCoLC)317249552|z(OCoLC)213775632 
040    DNLM/DLC|beng|cDLC|dNLM|dC#P|dYDXCP|dBAKER|dIG#|dSTJ 
042    pcc 
049    STJP 
050 00 RM301.25|b.H36 2009 
060 00 W1|bDR893B v.196 2009 
060 10 QV 771|bH2366 2009 
082 00 615/.19|222 
096    QV 771|bH236 2009 
245 00 Handbook of drug screening /|cedited by Ramakrishna 
       Seethala, Litao Zhang. 
250    Second edition. 
264  1 New York :|bInforma Healthcare,|c[2009] 
264  4 |c©2009 
300    xiii, 489 pages :|billustrations ;|c24 cm. 
336    text|btxt|2rdacontent 
337    unmediated|bn|2rdamedia 
338    volume|bnc|2rdacarrier 
490 1  Drugs and the pharmaceutical sciences ;|v196 
504    Includes bibliographical references and index. 
505 0  Key factors for successful high-throughput screening / 
       John G. Houston -- Critical components in high-throughput 
       screening : challenges and new trends / Litao Zhang, 
       Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-
       lead optimization strategies : a biology perspective to 
       conquer the valley of death / Anuradha Roy ... [et al.] --
       Signal detection platforms for screening in drug discovery
       / Ramakrishna Seethala -- Proteomic analysis in drug 
       discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- 
       Screening and characterization of g-protein-coupled 
       receptor ligands for drug discovery / Ge Zhang and Mary 
       Ellen Cvijic -- 
505 0  Nuclear hormone receptor screening in drug discovery / 
       Ramakrishna Seethala and Litao Zhang -- Emerging novel 
       high-throughput screening technologies for cell-based 
       assays / ILona Kariv ... [et al.] -- In vitro strategies 
       for ion channel screening in drug discovery / Ravikumar 
       Peri, Mark Bowlby, and John Dunlop -- Wheat from chaff : 
       general and mechanistic triage of screening hits for 
       enzyme targets / Mark R. Harpel -- Protein kinases and 
       phosphatases / Pirthipal Singh -- MicroRNA strategies in 
       drug discovery / Wishva B. Herath -- Strategies for 
       screening of biologic therapeutics / Ian Foltz and 
       Francesca Civoli -- 
505 0  Cryopreserved cells in functional cell-based HTS assays / 
       Geetha Shankar and Kirk McMillan -- High-content screening
       with a special emphasis on cytotoxicity and cell health 
       measurements Ralph J. Garippa and Ann F. Hoffman -- 
       Effective application of drug metabolism and 
       pharmacokinetics in drug discovery Sharon Diamond and 
       Swanny Yeleswaram -- Compound management for drug 
       discovery : an overview Moneesh Chatterjee and Martyn N. 
       Banks -- Practical approach to quantitative high 
       throughput screening Wei Zheng, Ke Liu, and James Inglese 
       -- Enabling the large-scale analysis of quantitative high-
       throughput screening data Noel T. Southall ... [et al.] --
       Application of nanobiotechnologies for drug discovery / 
       K.K. Jain. 
650  0 Drug development|vHandbooks, manuals, etc. 
650  0 Drugs|xTesting|vHandbooks, manuals, etc. 
650 12 Drug Evaluation, Preclinical|xmethods. 
700 1  Seethala, Ramakrishna,|d1947- 
700 1  Zhang, Litao. 
776 08 |iOnline version:|tHandbook of drug screening.|b2nd ed.
       |dNew York : Informa Healthcare, c2009|w(OCoLC)777256236 
830  0 Drugs and the pharmaceutical sciences ;|vv. 196. 
938    YBP Library Services|bYANK|n2790914 
938    Baker & Taylor|bBKTY|c249.95|d.00|i1420061682|n0007187253
       |sactive 
938    Ingram|bINGR|n9781420061680 
994    01|bSTJ