Description |
xix, 458 pages : illustrations ; 25 cm |
Bibliography |
Includes bibliographical references and index. |
Contents |
If it works, it works : pragmatic molecular discovery -- Empirical miracles : nature's precedents for empirical solutions -- Evolution's gift : natural somatic diversification and molecular design -- Evolution while you wait -- The blind protein maker -- The blind shaper of nucleic acids -- Evolving and creating recognition molecules -- Molecules small and large -- An empirical-rational loop forwards -- Exploring the limits. |
Summary |
"Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery."--BOOK JACKET. |
Subject |
Biochemistry -- Research.
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Drugs -- Design.
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Drug Discovery -- trends.
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Chemistry, Pharmaceutical -- methods.
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Combinatorial Chemistry Techniques -- methods.
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Evolution, Molecular.
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Molecular Structure.
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Quantitative Structure-Activity Relationship.
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ISBN |
9780470146828 cloth |
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0470146826 cloth |
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