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082 00 570.285|222 
084    BIO 110f|2stub 
084    WC 7700|2rvk 
084    WD 9200|2rvk 
092    570.28|bA454I 
100 1  Alon, Uri,|d1969- 
245 13 An introduction to systems biology :|bdesign principles of
       biological circuits /|cUri Alon. 
264  1 Boca Raton, FL :|bChapman & Hall/CRC,|c[2007] 
264  4 |c©2007 
300    xvi, 301 pages, 4 unnumbered pages of plates :
       |billustrations (some color) ;|c26 cm. 
336    text|btxt|2rdacontent 
337    unmediated|bn|2rdamedia 
338    volume|bnc|2rdacarrier 
490 1  Chapman & Hall/CRC mathematical and computational biology 
       series ;|v10 
504    Includes bibliographical references (pages 271-293) and 
       index. 
505 00 |gCh. 1.|tIntroduction --|gCh. 2.|tTranscription networks 
       : basic concepts --|gCh. 3.|tAutoregulation : a network 
       motif --|gCh. 4.|tThe feed-forward loop network motif --
       |gCh. 5.|tTemporal programs and the global structure of 
       transcription networks --|gCh. 6.|tNetwork motifs in 
       developmental, signal transduction, and neuronal networks 
       --|gCh. 7.|tRobustness of protein circuits : the example 
       of bacterial chemotaxis --|gCh. 8.|tRobust patterning in 
       development --|gCh. 9.|tKinetic proofreading --|gCh. 10.
       |tOptimal gene circuit design --|gCh. 11.|tDemand rules 
       for gene regulation --|gCh. 12.|tEpilogue : simplicity in 
       biology 
520 3  [Publisher-supplied data] This book presents recently 
       discovered design principles that govern the structure and
       behavior of biological networks such as gene circuits, 
       highlighting simple, recurring circuit elements that make 
       up the network. It provides a quantitative theory for 
       which circuits are found in a given environment and a 
       mathematical framework for understanding and even 
       designing biological circuits. The book requires only 
       basic mathematics and includes a review of the necessary 
       background material. It fills a significant need for a 
       textbook and introduction to the concepts, principles, and
       mathematical tools that will form the basis of future 
       developments in the field. 
650  0 Systems biology. 
650  0 Computational biology. 
650  0 Biological systems|xMathematical models. 
650 12 Gene Regulatory Networks. 
650 22 Systems Biology|xmethods. 
830  0 Chapman and Hall/CRC mathematical & computational biology 
       series ;|v10. 
856 42 |3Publisher description|uhttp://catdir.loc.gov/catdir/
       enhancements/fy0654/2005056902-d.html 
938    YBP Library Services|bYANK|n2268508 
938    Baker & Taylor|bBKTY|c54.95|d.00|i1584886420|n0006645544
       |sactive 
938    Ingram|bINGR|n9781584886426 
938    Brodart|bBROD|n05811694|c$49.95 
994    01|bSTJ