Introduction : Illicit drugs and government control / Ronald Hamowy -- Part I. The effects of prohibition -- The history of legislative control over opium, cocaine, and their derivatives / D.F. Musto -- Curing the drug-law addiction - The harmful side effects of legal prohibition / Randy E. Barnett -- The need for reform of international narcotics laws / Arnold S. Trebach -- Drugs and United States foreign policy / Jonathan Marshall -- Part II. Medical research concerning illicit substances -- Medical uses of illicit drugs / Lester Grinspoon and James B. Bakalar -- Cocaine, marijuana, and the meanings of addiction / Robert Byck -- The use and misuse of intoxicants - Factors in the development of controlled use / Norman E. Zinberg -- Part III. Policy reform : Evidence and ethics -- The market for heroin before and after legalization / Robert J. Michaels -- The morality of drug controls / Thomas Szasz.