The Nature of the Problem -- Laying the Groundwork -- Characteristics That Make Somatic Diseases Difficult to Detect -- Patterns in Time -- The Clinical Interview -- The History of the Present Illness -- Specific Physical Signs and Symptoms -- Classical Presentations: Focal Signs, Dementia, and Delirium -- Specific Mental Signs and Symptoms -- Important Aspects of the Patient Assessment: A Second Look -- Extended Clinical Vignettes: Working with Patients.