LEADER 00000cam 2200000 i 4500 001 ocn671465409 003 OCoLC 005 20140411150055.0 008 101019s2011 flua b 001 0 eng 010 2010044822 016 7 101544647|2DNLM 016 7 015600807|2Uk 019 587104341 020 9781439810675|q(hardcover : alkaline paper) 020 1439810672|q(hardcover : alkaline paper) 035 (OCoLC)671465409|z(OCoLC)587104341 040 DNLM/DLC|beng|erda|cDLC|dYDX|dBTCTA|dYDXCP|dNLM|dCDX |dUKMGB|dCLU|dOCLCQ|dCHVBK|dOCLCF|dSTJ 042 pcc 049 STJP 050 00 RS431.R34|bW55 2011 060 00 2011 B-810 060 04 WN 615|bW724r 2011 060 10 WN 415 082 00 615.8/424|222 096 WN 415|bW724R 2011 100 1 Williams, Lawrence E.,|eauthor. 245 10 Radiopharmaceuticals :|bintroduction to drug evaluation and dose estimation /|cLawrence E. Williams. 260 Boca Raton, FL :|bCRC Press,|c©2011. 300 xxi, 304 pages :|billustrations ;|c24 cm 336 text|btxt|2rdacontent 337 unmediated|bn|2rdamedia 338 volume|bnc|2rdacarrier 504 Includes bibliographical references and index. 520 "This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT /CT and PET/CT"--Provided by publisher. 598 STJONEW 650 0 Radiopharmaceuticals. 650 12 Radiopharmaceuticals. 650 22 Clinical Trials as Topic. 650 22 Radiopharmaceuticals|xadministration & dosage. 938 Baker and Taylor|bBTCP|nBK0008858783 938 YBP Library Services|bYANK|n3312754 938 Coutts Information Services|bCOUT|n12709774 994 01|bSTJ
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