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Title The biology of the first 1,000 days / edited by Crystal D. Karakochuk [and three others].

Publication Info. Boca Raton [Florida] ; London [England] ; New York : CRC Press, 2018.


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Description 1 online resource (519 pages).
Series Oxidative stress and disease
Oxidative stress and disease.
Contents Cover; Half Title; Title Page; Copyright Page; Table of Contents; Series Preface ; Oxidative Stress in Health and Disease ; Preface ; Acknowledgments ; Editors ; Contributors ; Section I : Introduction; Chapter 1: The Importance of the First 1,000 Days ; Epidemiological Burden and Distribution of the Problem of Malnutrition ; Window of Opportunity ; The First 300 Days ; The Next 700 Days of Life ; Risk Factors for Child Stunting ; Public Health and Economic Importance of Nutrition and the First 1,000 Days ; Conclusion ; References ; Section II : What Is Normal Growth?
Chapter 2: World Health Organization Child Growth Standards Introduction ; Rationale for Developing the World Health Organization Child Growth Standards ; Design of the WHO Multicentre Growth Reference Study ; Construction of the WHO Child Growth Standards ; Innovative Aspects of the WHO Child Growth Standards ; Implications of Adopting the WHO Child Growth Standards for Public Health and Clinical Practice ; Complementary Charts for Fetuses, Newborns by Gestational Age, Preterm Infants, and Children Older Than 5 Years of Age ; Conclusion ; Notes ; References.
Section III : Nutritional Requirements in the Life StagesChapter 3: Nutrient Requirements and Recommendations during Pregnancy ; Introduction ; Requirements and Recommendations for Macronutrients during Pregnancy ; Energy ; Fat and Fatty Acids ; Protein ; Carbohydrates ; Requirements and Recommendations for Mineral Intakes During Pregnancy ; Iron ; Zinc ; Iodine ; Calcium ; Other Minerals ; Requirements and Recommendations for Vitamin Intakes during Pregnancy ; Vitamin A ; Vitamin D ; Folate ; Vitamin B12 ; Other Vitamins.
Recommendations for Avoidance and Limitation of Intakes during Pregnancy Toxic Heavy Metals, Contaminants, and Food Additives ; Caffeine, Alcohol, and Other Intoxicants ; Conclusion and Future Directions for Research ; References ; Chapter 4: Nutrient Requirements during Lactation ; Introduction ; Energy ; Fatty Acids ; Protein ; Carbohydrate ; Vitamin A ; B Vitamins ; Vitamin C ; Vitamin D ; Calcium ; Iron ; Iodine ; Zinc ; Copper and Selenium ; Conclusion ; References ; Chapter 5: Nutrient Requirements of Infants and Young Children ; Nutrition Considerations for Young Infants (0-6 Months).
Nutrition Considerations for Older Infants and Toddlers (6-24 months) Contemporary Health Issues Related to Complementary Feeding Practices ; Complementary Feeding and Allergy Prevention ; Obesity Risk and Protein Intake ; Neurocognitive Development and Early Nutrition ; Conclusion ; References ; Section IV : Endocrinology in the Regulation of Growth; Chapter 6: Hormonal Regulation during Lactation and Human Milk Production ; The Hormones of Lactation: Actions and Patterns of Secretion ; Actions of Prolactin (PRL) ; Actions of Oxytocin (OT).
Summary The first 1,000 days, from conception to 2 years of age, is a critical window of growth and development. Exposures to dietary, environmental, hormonal, and other stressors during this period have been associated with an increased risk of adverse health outcomes. Researchers using cell culture, animal models, and humans have identified this time as a period of rapid physiological change and plasticity with significant potential for lasting effects. As such, interventions during the first 1,000 days will have the greatest impact on outcomes, particularly in low- and middle-income countries where the need is greatest. To date, there is no single resource that compiles our knowledge of the biology of the first 1,000 days. Our knowledge and understanding of the biology behind the first 1,000 days is still limited. This greater understanding is helping us inform effective nutrition policy and programming. The strength of this book lies in its cross- disciplinary nature that encompasses the full range of human biology, providing a more holistic perspective during this critical time frame. Moreover, we have broadened the scope and included important periods before and after the 1,000 days. We have designed this book as a comprehensive resource for those involved in global health and nutrition policy, strategy, programming, or research. This book will also be a resource for students learning about nutrition and health across the 1,000 days. The book includes an exceptional group of contributors who are experts in their given fields. As biology underlies the core of each discussion, it allows the readers to answer the what and why, and, we hope, the how for new discovery research and more effective interventions. Each chapter in this volume provides insight into a specific life stage, disease state, nutrient, and stressor in the first 1,000 days. As such, each chapter can be read independently, providing a comprehensive overview of that subject. However, there is continuity between chapters allowing this collection of chapters to be read cover to cover. The first chapters set the stage, providing a succinct resource to understand the well-established biological mechanisms that underlie growth regulation and nutrient recommendations throughout the first 1,000 days. The next chapters move on to the evidence behind nutrition-specific and nutrition-sensitive interventions to combat adverse outcomes and disease states in the first 1,000 days. This book also features emerging research areas, such as the gut microbiome, environmental enteric dysfunction, and the role of epigenetics in health and development. The final chapter pushes the boundaries of discovery research, exploring novel areas such as proteomics and metabolomics, and how insults such as environmental enteric dysfunction affect metabolism in the first 1,000 days. We approached this book with the ambition to shed more light on the biology during 1,000 days, but there was also a need to put the biology into a broader context of nutrition and health. There are still many gaps in our understanding of the biology of the first 1,000 days. It is only by bridging this knowledge gap through research that we can inform effective interventions to improve outcomes during the first 1,000 days.
Bibliography Includes bibliographical references.
Subject Pregnancy.
Pregnancy -- Complications.
Pregnancy -- physiology. (DNLM)D011247Q000502
Pregnancy Trimester, First -- physiology. (DNLM)D011261Q000502
Maternal Nutritional Physiological Phenomena. (DNLM)D039382
Fetal Development. (DNLM)D047109
Nutritional Requirements. (DNLM)D009751
Pregnancy Complications -- etiology. (DNLM)D011248Q000209
Pregnancy Complications -- prevention & control. (DNLM)D011248Q000517
MEDICAL -- Gynecology & Obstetrics.
Clinical and internal medicine.
Gynaecology and obstetrics.
Pregnancy. (OCoLC)fst01075102
Pregnancy -- Complications. (OCoLC)fst01075106
Genre/Form Electronic book.
Added Author Karakochuk, Crystal D., editor.
Other Form: Print version: Biology of the first 1,000 days. Boca Raton [Florida] ; London [England] ; New York : CRC Press, 2018 (DLC) 2017013475
ISBN 1498756808 (ebk)
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