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Title Anesthetic pharmacology / edited by Alex S. Evers, Mervyn Maze, Evan D. Kharasch.

Publication Info. Cambridge ; New York : Cambridge University Press, [2011]


Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Reference Material  PHARM QV 81 A579 2011    In-Library Use Only
Edition Second edition.
Description xv, 1194 pages : illustrations ; 29 cm.
Series Cambridge medicine
Cambridge medicine.
Bibliography Includes bibliographical references and index.
Contents Section 1. Principles of Drug Action: 1. Pharmacodynamic principles of drug action; 2. G-protein coupled receptors; 3. Ion channels; 4. Other signalling pathways; 5. Principles of pharmacokinetics; 6. Principles of drug biotransformation; 7. Drug transport and transporters; 8. Target-controlled infusions and closed-loop administration; 9. Alternate routes of drug administration; 10. Principles of pharmacogenetics; 11. Pharmacodynamic drug-interactions in anesthetic practice; 12. Pharmacoeconomics; Section 2. Physiologic Substrates of Drug Action: 13. Sleep and consciousness; 14. Synaptic transmission; 15. Memory, learning and cognition; 16. Mechanisms of pain transmission and transduction; 17. Generation and propagation of action potentials; 18. Neuromuscular junction; 19. Vascular reactivity; 20. Cardiac rhythm; 21. Myocardial performance; 22. Autonomic function; 23. Immunity and inflammation; Section 3I. Essential Drugs in Anesthetic Practice: 24. Mechanisms of anesthetic action; 25. Pharmacokinetics of inhaled anesthetics; 26. Clinical pharmacology of inhaled anesthetics; 27. Pharmacokinetics of intravenous anesthetics; 28. Clinical pharmacology of intravenous anesthetics; 29. Benzodiazepines; 30. Alpha2 Agonists and other sedatives and amnestics; 31. Mechanisms of action of opioids; 32. Pharmacokinetics of opioids; 33. Clinical pharmacology of opioids; 34. Nonsteroidal anti-inflammatory drugs; 35. Other ion channel and receptor ligands for analgesia; 36. Local anesthetics;
37. Anticonvulsant and antipsychotic drugs; 38. Neuromuscular blocking agents; 39. Drugs for reversal of neuromuscular blockade; 40. Sympathomimetics and sympatholytic drugs; 41. Parasympathomimetic and parasympatholytic drugs; 42. Beta-blockers and other adrenergic receptor antagonists; 43. Antiarrhythmic drugs; 44. Positive inotropic drugs; 45. Vasodilators; 46. Calcium channel blockers; 47. Bronchodilators; 48. Pulmonary vasodilators; 49. Renal protection and pharmacology; 50. Fluids and electrolytes; 51. Corticosteroids and anti-inflammatory agents; 52. Antirejection drugs and immunosuppressants; 53. Antimotility and antisecretory agents; 54. Antiemetics; 55. Insulin and antihyperglycemic agents; 56. Nutritional pharmacology; 57. Drugs affecting coagulation and platelet function; 58. Obstetric pharmacology; 59. Antimicrobial therapy; Section 4. Clinical Applications : Evidence Based Anesthesia practice: 60. Preoperative management; 61. Induction of anesthesia; 62. Maintenance and emergence from anesthesia; 63. Management of sedation, analgesia and delirium; 64. Postoperative analgesia; 65. Control of blood pressure and vascular tone; 66. Cardiac protection and pharmacologic management of myocardial ischemia; 67. Management of patients with chronic alcohol or drug use; 68. Drug allergy and treatment; 69. Pediatric pharmacology; 70. Geriatric pharmacology; 71. Emerging concepts of anesthetic neuroprotection and neurotoxicity.
Summary "In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, second edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period"--Provided by publisher.
Subject Anesthetics.
Anesthetics -- pharmacology.
Analgesics -- pharmacology.
Added Author Evers, Alex S.
Maze, M. (Mervyn)
Kharasch, Evan D.
ISBN 9780521896665 hardback
0521896665 hardback
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