Includes bibliographical references (pages 229-236) and index.
Contents
Seduced by drug discovery -- The small molecules of life -- Proteins : molecular wonders in three dimensions -- Proteins perform multiple functions : enzymes, receptors, ion channels -- Drug discovery and development : the road from an idea to promoting human health -- Finasteride : the Gary and Jerry show -- Basic research, snake venoms, and ACE inhibitors : Ondetti, Cushman, and Patchett -- Statins : protection against heart attacks and strokes -- The perils of primaxin -- Avermectins : molecules of life battle parasites -- Fludalanine : nice try but no hallelujah -- Diabetes breakthrough : Januvia and Janumet.