An oasis of humanity -- Genes and behaviour -- The first smile -- Down Syndrome: what's in a name? -- Williams Syndrome -- Rubenstein-Taybi Syndrome -- Fragile X Syndrome: a constitutional threshold experience -- Foetal Alcohol Syndrome -- Prader-Willi Syndrome -- Angelman Syndrome -- Angelman and Prader-Willi Syndromes: a polarity -- Wolf-Hirschhorn Syndrome -- The Sun Cross.