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Book Cover
Author Shargel, Leon, 1941- author.

Title Applied biopharmaceutics & pharmacokinetics / Leon Shargel, Andrew B.C. Yu.

Publication Info. New York : McGraw-Hill Education, [2016]


Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Internet  WORLD WIDE WEB E-BOOK MCGRAW    Downloadable
University of Saint Joseph patrons, please click here to access this McGraw-Hill resource
Edition Seventh edition.
Description 1 online resource : illustrations.
Bibliography Includes bibliographical references and index.
Contents Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- Biostatistics -- One compartment open model : IV bolus injection -- Multicompartmental models : IV bolus injection -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Renal and hepatic elimination of drugs -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified release drug products and drug devices -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetic and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Application of pharmacokinetics in specific populations -- Dosage adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moment and noncompartmental analysis.
Subject Biopharmaceutics.
Drug Administration Routes.
Models, Chemical.
Biopharmaceutics. (OCoLC)fst00832650
Pharmacokinetics. (OCoLC)fst01060250
Added Author Yu, Andrew B. C., 1945- author.
Note Applied biopharmaceutics and pharmacokinetics
ISBN 9780071830935 (electronic bk.)
0071830936 (MHID)
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