Edition |
Seventh edition. |
Description |
1 online resource : illustrations. |
Bibliography |
Includes bibliographical references and index. |
Contents |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- Biostatistics -- One compartment open model : IV bolus injection -- Multicompartmental models : IV bolus injection -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Renal and hepatic elimination of drugs -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified release drug products and drug devices -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetic and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Application of pharmacokinetics in specific populations -- Dosage adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moment and noncompartmental analysis. |
Subject |
Biopharmaceutics.
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Pharmacokinetics.
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Biopharmaceutics.
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Pharmacokinetics.
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Drug Administration Routes.
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Models, Chemical.
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Biopharmaceutics. (OCoLC)fst00832650
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Pharmacokinetics. (OCoLC)fst01060250
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Added Author |
Yu, Andrew B. C., 1945- author.
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Note |
Applied biopharmaceutics and pharmacokinetics |
ISBN |
9780071830935 (electronic bk.) |
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0071830936 (MHID) |
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