LEADER 00000cam 2200661Ii 4500 001 on1010748198 003 OCoLC 005 20200419055522.7 006 m o d 007 cr cnu---unuuu 008 171108s2018 sz a o 001 0 eng d 015 GBB953107|2bnb 016 7 019301978|2Uk 019 994639635|a994786290 020 9783319656397|q(electronic book) 020 3319656392|q(electronic book) 020 |z9783319656380|q(print) 020 |z3319656384|q(print) 024 7 10.1007/978-3-319-65639-7|2doi 035 (OCoLC)1010748198|z(OCoLC)994639635|z(OCoLC)994786290 037 com.springer.onix.9783319656397|bSpringer Nature 040 GW5XE|beng|erda|epn|cGW5XE|dYDX|dBTCTA|dBDX|dVLB|dOCLCF |dUAB|dMERER|dYDX|dOCLCQ|dU3W|dCAUOI|dSNK|dJG0|dOCLCQ|dCOO |dLVT|dC6I|dOCLCQ|dUKMGB|dOCLCQ|dOCLCO|dOCLCA|dESU|dOCLCA 049 STJJ 050 4 QD474|b.R67 2018eb 060 4 2018 D-600 060 4 QU 55 082 04 541/.2242|223 245 00 Self-assembled molecules - new kind of protein ligands : |bsupramolecular ligands /|cIrena Roterman, Leszek Konieczny, editors. 264 1 Cham, Switzerland :|bSpringer Open,|c2018. 264 4 |c©2018 300 1 online resource (xii, 136 pages) :|billustrations 336 text|btxt|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 500 Includes index. 505 0 Supramolecular systems as protein ligands -- Supramolecular Congo Red as Specific Ligand of Antibodies Engaged in Immune Complex -- Protein Conditioning for Binding Congo Red and Other Supramolecular Ligands -- Metal Ions Introduced to Proteins by Supramolecular Ligands -- Possible Mechanism of Amyloidogenesis of V Domains -- Supramolecular Structures as Carrier Systems Enabling the Use of Metal Ions in Antibacterial Therapy -- Congo Red Interactions with Single-Walled Carbon Nanotubes. 506 Open access.|5GW5XE 520 This book is an open access under a CC BY license. The subject of this book relates to protein ligands with particular structural and complexation properties. They are composed of self-assembled molecules, capable of penetrating as a unit into proteins outside the binding site. The ribbon-like supramolecular system only permits the penetration of self-assembled molecules into the protein-body and formation of stable complexes. Supramolecular Congo red and similar compounds fit these requirements. Destabilized protein fragments enable the penetration of such ligands, with susceptibility to supramolecular ligand binding often associated with protein function. As a result, complexation modifies their functional effects. The activity of enzymes is inhibited by arresting them in the complexed state, but "naturally irreversible" complexation as in the case of immune complexation, is enhanced instead. This property offers many attractive possibilities of using supramolecular ligands as described in this book. 588 0 Print version record. 590 SpringerLink|bSpringer Nature Open Access eBooks 650 0 Ligands. 650 0 Protein binding. 650 0 Biochemistry. 650 7 Biochemistry.|2fast|0(OCoLC)fst00831961 650 7 Ligands.|2fast|0(OCoLC)fst00998466 650 7 Protein binding.|2fast|0(OCoLC)fst01079673 650 12 Carrier Proteins. 650 22 Congo Red. 650 22 Ligands. 650 22 Models, Molecular. 650 22 Coloring Agents. 700 1 Roterman, Irena,|eeditor. 700 1 Konieczny, Leszek,|eeditor. 776 08 |iPrint version:|tSelf-assembled molecules - new kind of protein ligands.|d[S.l.] : Springer Open, 2018|z3319656384 |w(DLC) 2017953533|w(OCoLC)994786290 914 on1010748198 994 92|bSTJ
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