LEADER 00000cam  2200541Ii 4500 
001    ocn881869810 
003    OCoLC 
005    20150831151134.0 
008    140627s2015    nyua     b    001 0 eng d 
019    882187113 
020    0142181846 
020    9780142181843|q(pbk.) 
035    (OCoLC)881869810|z(OCoLC)882187113 
040    YDXCP|beng|erda|cYDXCP|dOCLCQ|dBTCTA|dBDX|dEXR|dOCLCF|dGWV
043    e-gx--- 
049    GWVA 
092    616.9792|bH742c 2015 
100 1  Holt, Nathalia,|d1980-|eauthor. 
245 10 Cured :|bthe people who defeated HIV /|cNathalia Holt. 
264  1 New York, New York :|bPlume, Published by the Penguin 
       Group,|c2015. 
300    xxi, 313 pages :|billustrations ;|c21 cm 
336    text|btxt|2rdacontent 
337    unmediated|bn|2rdamedia 
338    volume|bnc|2rdacarrier 
500    First published in the United States of America by Dutton,
       2014. 
504    Includes bibliographical references and index. 
505 0  A doctor, two patients, and some tests. The good doctor in
       denial ; A visit with the family doctor ; Death sentence? 
       -- The disease, a drug, and its industry. Viral Trojan 
       horse ; A weapon from the war on cancer ; The days of 
       acting up ; Recognizing a global pandemic ; From the one 
       percent ; But, Doctor, I don't feel sick ; The Delta 32 
       Mutation ; Calling all elite controllers ; Treatment in 
       hiding -- Treating the Berlin patients. The second 
       diagnosis ; The compassionate use exemption ; Three deadly
       diseases move in ; The comfort of family and strangers ; 
       Timing ; Transplanting ; "Perhaps we have eradicated HIV" 
       ; An unexciting recovery -- The cure. Trials ; Proof of 
       principle ; The good doctor in court ; Not even surprising
       ; The promise kept ; A child cured-- so what? ; Zinc 
       finger snap ; The abused, the respected, the relentless. 
520    A young molecular biologist at the forefront of HIV 
       research, Nathalia Holt tells the historic, multilayered, 
       and compassionate story of two patients--each known in 
       medical literature as the Berlin Patient--and their young 
       research-minded doctors. The backdrop is nothing less than
       a revolution in cultural attitudes and medical thinking. 
       These two patients' disparate cures came twelve years 
       apart: the first in 1996 from an experimental cancer drug,
       the other in 2008 from a bone marrow transplant of cells 
       with a particular genetic mutation. Holt connects the 
       molecular dots of these two cases for the first time, 
       providing insight into one of the most important medical 
       breakthroughs of our generation.--From publisher 
       description. 
650  0 HIV infections|xTreatment|zGermany|zBerlin. 
650  0 Gene therapy|zGermany|zBerlin|xHistory. 
650  7 Gene therapy.|2fast|0(OCoLC)fst00939638 
650  7 HIV infections|xTreatment.|2fast|0(OCoLC)fst00949907 
650 12 HIV Infections|xtherapy|zGermany. 
650 22 Anti-HIV Agents|xhistory|zGermany. 
650 22 Anti-HIV Agents|xtherapeutic use|zGermany. 
650 22 Genetic Therapy|xhistory|zGermany. 
650 22 History, 20th Century|zGermany. 
650 22 History, 21st Century|zGermany. 
650 22 Hydroxyurea|xhistory|zGermany. 
650 22 Hydroxyurea|xtherapeutic use|zGermany. 
650 22 Treatment Outcome|zGermany. 
651  7 Germany|zBerlin.|2fast|0(OCoLC)fst01204829 
655  7 History.|2fast|0(OCoLC)fst01411628 
994    02|bGWV