| Edition |
Fourth edition / edited by Daan J.A. Crommelin, Robert D. Sindelar, Bernd Meibohm. |
| Description |
1 online resource. |
| Note |
Previous edition: New York: Informa Healthcare, 2008. |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Molecular Biotechnology: From DNA Sequence to Therapeutic Protein / Ronald S. Oosting -- Biophysical and Biochemical Analysis of Recombinant Proteins / Tsutomu Arakawa and John S. Philo -- Production and Purification of Recombinant Proteins / Farida Kadir, Paul Ives and Alfred Luitjens -- Formulation of Biotech Products, Including Biopharmaceutical Considerations / Daan J.A. Crommelin -- Pharmacokinetics and Pharmacodynamics of Peptide and Protein Therapeutics / Bernd Meibohm -- Immunogenicity of Therapeutic Proteins / Huub Schellekens and Wim Jiskoot -- Monoclonal Antibodies: From Structure to Therapeutic Application / John D. Davis and Rong Deng -- Genomics, Other "Omic" Technologies, Personalized Medicine, and Additional Biotechnology-Related Techniques / Robert D. Sindelar -- Dispensing Biotechnology Products: Handling, Professional Education, and Product Information / Peggy Piascik and Val Adams -- Economic Considerations in Medical Biotechnology / Eugene M. Kolassa and Tushar B. Padwal -- Regulatory Framework for Biosimilars / Vinod P. Shah and Daan J.A. Crommelin -- Insulin / John M. Beals and Michael R. DeFelippis -- Follicle-Stimulating Hormone / Tom Sam, Renato de Leeuw and Gijs Verheijden -- Human Growth Hormone / Le N. Dao, Barbara Lippe and Michael Laird -- Recombinant Coagulation Factors and Thrombolytic Agents / Nishit B. Modi -- Recombinant Human Deoxyribonuclease I / Robert A. Lazarus and Jeffrey S. Wagener -- Monoclonal Antibodies in Cancer / Amy Grimsley and Katherine S. Shah -- Hematopoietic Growth Factors: Focus on Erythropoiesis-Stimulating Agents / Juan Jose Pérez-Ruixo and Andrew T. Chow -- Monoclonal Antibodies in Solid Organ Transplantation / Nicole A. Pilch and Holly B. Meadows -- Monoclonal Antibodies and Antibody-Based Biotherapeutics in Inflammatory Diseases / Honghui Zhou and Zhenhua Xu -- Interferons and Interleukins / Jean-Charles Ryff and Sidney Pestka -- Vaccines / Wim Jiskoot and Gideon F.A. Kersten -- Oligonucleotides / Raymond M. Schiffelers and Enrico Mastrobattista -- Gene Therapy / Hao Wu and Ram I. Mahato -- Stem Cell Technology / Colin W. Pouton. |
| Summary |
Setting the standard for modern biopharmaceutical education, the new Fourth Edition is a completely revised text to reflect the rapid growth in the importance of biopharmaceuticals and the techniques of biotechnologies to modern medicine and the life sciences. The editors have provided a well-balanced framework for introductory as well as more detailed education in various aspects of pharmaceutical biotechnology and the production, biopharmaceutics, and clinical pharmacology of biotechnology-produced drugs. The new edition improves upon the strong chapters of previous editions, adding emergent trends and cutting-edge advances as well as new graphic illustrations and new authors. The textbook includes key concepts at the foundation of the technology relevant for protein therapeutics including molecular biology, production and analysis procedures, formulation development, pharmacokinetics and pharmacodynamics, and immunogenicity, as well as chapters dealing with regulatory, economic, and pharmacy practice considerations. The Fourth Edition brings an exciting and fundamental reorganization of the text, now structured into two sections: 1) an initial basic science and general features section; and 2) a section profiling the various therapeutic classes of biologics, including gene therapy. Additionally, reorganization of the chapters examining the properties and applications of monoclonal antibodies, and oligonucleotides and siRNA has enhanced these important concepts in the text. A completely new chapter has been added on cell-based technologies. The Fourth Edition continues the popular self-assessment questions after each chapter to reinforce understanding of practical pharmaceutical applications, making this an indispensable text for self-study, the biopharmaceutical classroom, as well as for professional reference in practice or industry. |
| Note |
Print version record. |
| Subject |
Pharmaceutical biotechnology.
|
|
Pharmaceutical Preparations.
|
|
Technology, Pharmaceutical.
|
|
Biotechnology, Pharmaceutical.
|
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Pharmaceutical biotechnology. (OCoLC)fst01060106
|
| Genre/Form |
Electronic books.
|
| Added Author |
Crommelin, D. J. A. (Daan J. A.), editor.
|
|
Sindelar, Robert D., editor.
|
|
Meibohm, Bernd, editor.
|
| Other Form: |
Print version: Pharmaceutical biotechnology. Fourth edition 9781461464853 (OCoLC)829056054 |
| ISBN |
9781461464860 (electronic bk.) |
|
1461464862 (electronic bk.) |
| Standard No. |
10.1007/978-1-4614-6486-0 doi |
|
