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Title Structure-based drug discovery : an overview / edited by Roderick E. Hubbard.

Publication Info. Cambridge, UK : RSC Pub., [2006]
©2006

Copies

Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Reference Material  PHARM QV 744 S927 2006    In-Library Use Only
Description xvi, 261 pages : illustrations ; 24 cm.
Series RSC biomolecular sciences
RSC biomolecular sciences.
Bibliography Includes bibliographical references and index.
Contents 3D structure and the drug discovery process / Roderick E. Hubbard -- Structure determination : crystallography for structure-based drug discovery / David G. Brown and Maria M. Flocco -- Molecular modelling / Xavier Barril and Robert Soliva -- Applications of NMR in structure-based drug discovery / Ben Davis and Julia Hubbard-- Fragment screening : an introduction / Andrew R. Leach, Michael M. Hann, Jeremy N. Burrows and Ed Griffen -- Iterative structure-based screening of virtual chemical libraries and Factor Xa : finding the orally available antithrombotic candidate LY517717 / John W. Liebeschuetz, Stuart D. Jones, Michael R. Wiley and Steven C. Young -- Anti-influenza drugs from neuraminidase inhibitors -- Isoform specificity : the design of estrogen receptor-[beta] selective compounds / Peter Colman.
Summary 'Structure-Based Drug Discovery' is a collection of methods which exploit the ability to determine and analyse the three-dimensional structure of biological molecules. These methods have been adopted and enhanced to improve the speed and quality of drug discovery.
Subject Drug Design.
Models, Molecular.
Structure-Activity Relationship.
Drugs -- Design.
Drugs -- Structure-activity relationships.
Added Author Hubbard, R. E.
Royal Society of Chemistry (Great Britain)
Other Form: Online version: Structure-based drug discovery. Cambridge, UK : RSC Pub., c2006 (OCoLC)607848153
ISBN 9780854043514
0854043519
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