Description |
xvi, 261 pages : illustrations ; 24 cm. |
Series |
RSC biomolecular sciences |
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RSC biomolecular sciences.
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Bibliography |
Includes bibliographical references and index. |
Contents |
3D structure and the drug discovery process / Roderick E. Hubbard -- Structure determination : crystallography for structure-based drug discovery / David G. Brown and Maria M. Flocco -- Molecular modelling / Xavier Barril and Robert Soliva -- Applications of NMR in structure-based drug discovery / Ben Davis and Julia Hubbard-- Fragment screening : an introduction / Andrew R. Leach, Michael M. Hann, Jeremy N. Burrows and Ed Griffen -- Iterative structure-based screening of virtual chemical libraries and Factor Xa : finding the orally available antithrombotic candidate LY517717 / John W. Liebeschuetz, Stuart D. Jones, Michael R. Wiley and Steven C. Young -- Anti-influenza drugs from neuraminidase inhibitors -- Isoform specificity : the design of estrogen receptor-[beta] selective compounds / Peter Colman. |
Summary |
'Structure-Based Drug Discovery' is a collection of methods which exploit the ability to determine and analyse the three-dimensional structure of biological molecules. These methods have been adopted and enhanced to improve the speed and quality of drug discovery. |
Subject |
Drug Design.
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Models, Molecular.
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Structure-Activity Relationship.
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Drugs -- Design.
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Drugs -- Structure-activity relationships.
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Added Author |
Hubbard, R. E.
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Royal Society of Chemistry (Great Britain)
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Other Form: |
Online version: Structure-based drug discovery. Cambridge, UK : RSC Pub., c2006 (OCoLC)607848153 |
ISBN |
9780854043514 |
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0854043519 |
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