| Edition |
Fifth edition. |
| Description |
xx, 892 pages : illustrations ; 24 cm |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model : intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Hepatic elimination of drugs -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficiancy -- Modified-release drug products -- Targeted drug delivery systems and biotechnological products -- Relationship between pharmacokinietics and pharmacodynamics -- Application of pharmacokinietics in clinical situations -- Dose adjustment in renal and hepatic disease -- Physiological pharmacokinetic models, mean residence time, and statistical moment theory -- Appendix A. Statistics -- Appendix B. Application of computers in pharmacokinetics -- Appendix C. Ethical considerations -- Appendix D. Solutions to frequently asked questions (FAQ) and learning questions -- Appendix E. Popular drugs and pharmacokinetic parameters. |
| Subject |
Biopharmaceutics.
|
|
Pharmacokinetics.
|
|
Biopharmaceutics.
|
|
Models, Chemical.
|
|
Pharmacokinetics.
|
| Added Author |
Wu-Pong, Susanna.
|
|
Yu, Andrew B. C., 1945-
|
| Added Title |
Applied biopharmaceutics and pharmacokinetics |
| ISBN |
0071375503 |
|
9780071375504 |
|
0071375511 |
|
9780071375511 |
|
