Edition |
Second edition. |
Description |
xvi, 665 pages : illustrations ; 24 cm. |
Series |
Drugs and the pharmaceutical sciences ; 156 |
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Drugs and the pharmaceutical sciences ; 156.
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Bibliography |
Includes bibliographical references and index. |
Contents |
Historical aspects of pharmacogenetics / Werner Kalow -- Pharmacogenomics and the promise of personalized medicine / Vural Ozdemir and Bernard Lerer -- Pharmacogenetics of drug metabolism: two clinically important polymorphic enzymes, CYP2D6 and TPMT / Georgios Panagiotidis and Leif Bertilsson -- Receptors / Wendell W. Weber -- Pharmacogenetics of drug transporters / Catia Marzolini, Rommel G. Tirona, and Richard B. Kim -- Variability in induction of human drug metabolizing enzymes / Allan B. Okey -- Pharmacogenetics and cardiac ion channels / Dan M. Roden -- Interethnic differences in drug response / Werner Kalow -- Clinical perspectives / Urs A. Meyer and David A. Flockhart -- Regulatory perspectives on pharmacogenomics / Lawrence J. Lesko and Janet Woodcock -- Tools of the trade: the technologies and challenges of pharmacogenetics / Glenn A. Miller -- Technologies for the analysis of single nucleotide polymorphisms - an overview / Denis M. Grant -- Molecular diagnostics / Tracy L. Stockley and Peter N. Ray -- |
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Metabonomics / Lois D. Lehman-McKeeman -- Multiplex minisequencing on microarrays: application to pharmacogenetics of antihypertensive drug response / Ulrika Liljedahl and Ann-Christine Syvänen -- MALDI-TOF MS: applications in genomics / Martin Beaulieu ... [et al.] -- Gene expression analysis in pharmacogenetics and pharmacogenomics / Julius V. Halaschek-Wiener, Marco A. Marra, and Angela R. Brooks-Wilson -- Proteomics / Frank A. Witzmann and Mu Wang -- Haplotype structure and pharmacogenomics / Oliver G. McDonald and William E. Evans -- Pharmacoepigenetics: from basic epigenetics to therapeutic applications / James Flanagan and Arturas Petronis -- WWW bioinformatics resources / S.W. Tang and D.M. Helmeste -- Pharmacogenomics: applied bioinformatics chapter / Lyle D. Burgoon, Paul c. Boutros, and Timothy R. Zacharewski -- Mapping of disease loci / Glenys Thomson and Ana Maria Valdes -- Positional cloning and disease gene identification / Richard F. Wintle and Katherine A. Siminovitch -- Genome variation influencing gene copy number and disease / Lars Feuk ... [et al.] -- General conclusions and future directions / Werner Kalow and Arno G. Motulsky. |
Subject |
Pharmacogenomics.
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Pharmacogenetics.
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Drug Design.
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Added Author |
Kalow, Werner.
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Meyer, Urs A., 1938-
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Tyndale, Rachel, 1962-
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ISBN |
9781574448788 alkaline paper |
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1574448781 alkaline paper |
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