LEADER 00000cam  2200433Ia 4500 
001    ocn813225105 
003    OCoLC 
005    20140612122157.0 
008    030902s2012    enka   e b    001 0 eng   
020    9781107406919|q(paperback) 
020    1107406919|q(paperback) 
020    9780521621472|q(hardback) 
020    052162147X|q(hardback) 
035    (OCoLC)813225105 
035    (OCoLC)813225105 
040    AU@|beng|cAU@|dOCLCO|dYDXCP|dCNAUC 
049    CKEA 
050  4 RC537|b.P69223 2012 
082 04 616.85/27071|223 
100 1  Praag, Herman M. van|q(Herman Meïr),|d1929- 
245 10 Stress, the brain and depression /|cH. M. van Praag, E. R.
       de Kloet, J. van Os. 
250    1st pbk. ed. 
264  1 Cambridge ;|aNew York :|bCambridge University Press,
       |c2012. 
300    xii, 283 pages :|billustrations ;|c25 cm 
336    text|btxt|2rdacontent 
337    unmediated|bn|2rdamedia 
338    volume|bnc|2rdacarrier 
504    Includes bibliographical references and indexes. 
505 0  1. Diagnosing depression -- 2. Traumatic life events : 
       general issues -- 3. Life events and depression : 
       preliminary issues -- 4. Life events and depression : is 
       there a causal connection? -- 5. Genetics of depression --
       6. Gene-environment correlation and interaction in 
       depression -- 7. Monoamines and depression -- 8. Stress 
       hormones and depression -- 9. Stress, the brain and 
       depression. 
520    Can traumatic life events cause depression? Studies 
       generally point to a connection between adverse life 
       events and depression. However, establishing a causal 
       rather than associative connection, the key concern of 
       this 2004 book, is more problematic. What neurobiological 
       changes may be induced by stress and depression, and to 
       what extent do these changes correspond? The authors 
       structure their examination around three major themes: the
       pathophysiological role of stress in depression; whether 
       or not a subtype of depression exists that is particularly
       stress-inducible; and, finally, how best to diagnose and 
       treat depression in relation to its biological 
       underpinnings. 
650  0 Depression, Mental|xPathogenesis. 
650  0 Stress (Physiology)|xComplications. 
650  0 Brain|xEffect of stress on. 
700 1  Kloet, E. R. de. 
700 1  Os, J. van|q(Jim van) 
994    92|bCKE