| Edition |
Second edition. |
| Description |
xii, 374 pages : illustrations ; 27 cm. |
| Series |
Methods in molecular biology, 1064-3745 ; 910 |
|
Springer Protocols |
|
Methods in molecular biology (Clifton, N.J.) ; v. 910.
1064-3745
|
|
Springer protocols (Series) 1949-2448
|
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Cell perturbation screens for target identification by RNAi / Kubilay Demir and Michael Boutros -- Using functional genomics to identify drug targets : a Dupuytren's disease example / Mirela Sedic, Sandra Kraljevic Pavelic, and Karlo Hock -- Functional characterization of human genes from exon expression and RNA interference results / Dorothea Emig ... [et al.] -- Barcode sequencing for understanding drug-gene interactions / Andrew M. Smith ... [et al.] -- High-throughput sequencing of the methylome using two-base encoding / Christina A. Bormann Chung -- Applications and limitations of in silico models in drug discovery / Ahmet Sacan, Sean Ekins, and Sandhya Kortagere -- Compound Collection Preparation for Virtual screening / Cristian G. Bologa and Tudor I. Oprea -- Mapping between databases of compounds and protein targets / Sorel Muresan, Markus Sitzmann, and Christopher Southan -- Predictive cheminformatics in drug discovery : statistical modeling for analysis of micro-array and gene expression data / N. Sukumar, Michael P. Krein, and Mark J. Embrechts -- Advances in nuclear magnetic resonance for drug discovery / Laurel O. Sillerud and Richard S. Larson -- Human ABC transporter ABCG2 in cancer chemotherapy : drug molecular design to circumvent multidrug resistance / Toshihisa Ishikawa ... [et al.] -- Protein interactions : mapping interactome networks to support drug target discovery and selection / Javier De Las Rivas and Carlos Prieto -- Linking variants from genome-wide association analysis to function via transcriptional network analysis / Benjamin J. Keller, Sebastian Martini, and Viji Nair -- Models of excitation-contraction coupling in cardiac ventricular myocytes / M. Saleet Jafri -- Integration of multiple ubiquitin signals in proteasome regulation / Marta Isasa, Alice Zuin, and Bernat Crosas. |
| Subject |
Drug Design.
|
|
Computational Biology -- methods.
|
|
Drug Evaluation, Preclinical.
|
|
Genetic Techniques.
|
|
Microarray Analysis.
|
|
Pharmacogenetics -- methods.
|
|
Drug development.
|
|
High throughput screening (Drug development)
|
|
Drug development -- Data processing.
|
|
Protein engineering -- Computer simulation.
|
|
Bioinformatics.
|
|
Cheminformatics.
|
|
Combinatorial chemistry.
|
| Added Author |
Larson, Richard S.
|
| ISBN |
9781617799648 alkaline paper |
|
1617799645 alkaline paper |
|
