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LEADER 00000cam  2200661Ii 4500 
001    ocn904437712 
003    OCoLC 
005    20151118131304.0 
006    m     o  d         
007    cr cnu---unuuu 
008    150306s2015    sz a    ob    001 0 eng d 
019    908097412 
020    9783319121666|q(electronic bk.) 
020    3319121669|q(electronic bk.) 
024 7  10.1007/978-3-319-12166-6|2doi 
035    (OCoLC)904437712|z(OCoLC)908097412 
040    N$T|beng|erda|epn|cN$T|dN$T|dGW5XE|dE7B|dIDEBK|dUPM|dCOO
       |dYDXCP|dEBLCP|dDEBSZ|dSTJ 
049    STJJ 
050  4 RC280.L5 
072  7 HEA|x039000|2bisacsh 
072  7 MED|x014000|2bisacsh 
072  7 MED|x022000|2bisacsh 
072  7 MED|x112000|2bisacsh 
072  7 MED|x045000|2bisacsh 
082 04 616.99436|223 
099    PHARM WORLD WIDE WEB|aE-BOOK|aSPRINGER 
245 03 An information technology framework for predictive, 
       preventive and personalised medicine :|ba use-case with 
       hepatocellular carcinoma /|cLeonard Berliner, Heinz U. 
       Lemke, editors. 
264  1 Cham ;|aHeidelberg ;|aNew York :|bSpringer,|c[2015] 
264  4 |c©2015 
300    1 online resource :|billustrations. 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
490 1  Advances in predictive, preventive and personalised 
       medicine ;|vvolume 8 
504    Includes bibliographical references and indexes. 
505 0  Preface -- Introduction -- The Digital Patient Model and 
       Model Guided Therapy -- Hepatocellular Carcinoma and 
       Patient Assessment -- Imaging in Hepatocellular Carcinoma:
       Radiologic Assessment -- Imaging in Hepatocellular 
       Carcinoma: PET/CT -- Personalized Chemotherapy for 
       Hepatocellular Carcinoma -- Surgical Treatment for 
       Hepatocellular Carcinoma -- Minimally Invasive Therapies 
       for Hepatocellular Cancer: Ablation Technologies -- 
       Minimally Invasive Therapies for Hepatocellular Cancer: 
       Ablation Therapies -- Minimally Invasive Therapies for 
       Hepatocellular Cancer: Catheter-Directed Therapies -- 
       Radiation Oncology in the Treatment of Hepatocellular 
       Carcinoma -- Design of an IT System for Hepatocellular 
       Carcinoma -- Outlook and Expert Recommendations for 
       Predictive, Preventive and Personalized Medicine and 
       Hepatocellular Carcinoma. 
520    This book explores how PPPM, clinical practice, and basic 
       research could be best served by information technology 
       (IT). A use-case was developed for hepatocellular 
       carcinoma (HCC). The subject was approached with four 
       interrelated tasks: (1) review of clinical practices 
       relating to HCC; (2) propose an IT system relating to HCC,
       including clinical decision support and research needs; 
       (3) determine how a clinical liver cancer center can 
       contribute; and, (4) examine the enhancements and impact 
       that the first three tasks will have on the management of 
       HCC. An IT System for Personalized Medicine (ITS-PM) for 
       HCC will provide the means to identify and determine the 
       relative value of the wide number of variables, including 
       clinical assessment of the patient -- functional status, 
       liver function, degree of cirrhosis, and comorbidities; 
       tumor biology, at a molecular, genetic and anatomic level;
       tumor burden and individual patient response; medical and 
       operative treatments and their outcomes. 
588 0  Vendor-supplied metadata. 
650  0 Liver|xCancer|xInformation technology. 
650  0 Medicine, Preventive. 
650  0 Precision medicine. 
650  0 Liver|xCancer|xTreatment. 
650  0 Liver|xCancer. 
650  0 Oncology. 
650  7 HEALTH & FITNESS / Diseases / General.|2bisacsh 
650  7 MEDICAL / Clinical Medicine.|2bisacsh 
650  7 MEDICAL / Diseases.|2bisacsh 
650  7 MEDICAL / Evidence-Based Medicine.|2bisacsh 
650  7 MEDICAL / Internal Medicine.|2bisacsh 
655  0 Electronic books. 
700 1  Berliner, Leonard,|eeditor. 
700 1  Lemke, H. U.|q(Heinz U.),|eeditor. 
776 08 |iPrinted edition:|z9783319121659 
830  0 Advances in predictive, preventive and personalised 
       medicine ;|vvolume 8. 
994    02|bSTJ 
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