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LEADER 00000cam  22007097i 4500 
001    on1375084527 
003    OCoLC 
005    20240103213016.0 
006    m     o  d         
007    cr un|---aucuu 
008    230406s2023    sz a    ob    100 0 eng d 
019    1374815509|a1379506341|a1380479676|a1385501182|a1389623983
       |a1396916934 
020    9783031231759|q(electronic bk.) 
020    3031231759|q(electronic bk.) 
020    |z9783031231742|q(print) 
020    |z3031231740 
024 7  10.1007/978-3-031-23175-9|2doi 
035    (OCoLC)1375084527|z(OCoLC)1374815509|z(OCoLC)1379506341
       |z(OCoLC)1380479676|z(OCoLC)1385501182|z(OCoLC)1389623983
       |z(OCoLC)1396916934 
040    GW5XE|beng|erda|epn|cGW5XE|dYDX|dEBLCP|dOCLCF|dYDX|dOCLCO
       |dWSU|dOCLCO|dOCLCL 
049    STJJ 
050  4 RC280.H4|bT74 2021 
072  7 MJCL|2bicssc 
072  7 MED062000|2bisacsh 
072  7 MJCL|2thema 
082 04 616.99/491|223/eng/20230406 
111 2  Trends in Head and Neck Oncology (Conference)|n(8th :
       |d2021 :|cAmsterdam, Netherlands) 
245 10 Critical issues in head and neck oncology :|bkey concepts 
       from the Eighth THNO Meeting /|cJan B. Vermorken, Volker 
       Budach, C. René Leemans, Jean-Pascal Machiels, Piero 
       Nicolai, Brian O'Sullivan, editors. 
246 3  THNO Meeting 
264  1 Cham :|bSpringer,|c2023. 
300    1 online resource (ix, 365 pages) :|billustrations (some 
       color) 
336    text|btxt|2rdacontent 
337    computer|bc|2rdamedia 
338    online resource|bcr|2rdacarrier 
504    Includes bibliographical references. 
505 0  The gut microbiota and anticancer immunotherapy, Laurence 
       Zitvogel -- The bidirectional communication between tumor 
       cells and other components of the tumor microenvironment, 
       Phil Sloan -- Resistance mechanisms in immune checkpoint 
       inhibitors and radiotherapy and how to overcome this, 
       Kirsten Lauber -- DNA repair mechanisms as a new target in
       head and neck cancer, Kevin Harrington -- How to 
       standardize molecular profiling programs for routine 
       patient care, Ingeborg Tinhofer -- Novel immune oncology 
       targets beyond PD-1/PD-L1 in head and neck cancer, 
       Christophe Le Tourneau -- Analytic methods to understand 
       head and neck cancer evolution to guide therapeutic 
       approaches, Ben O'Leary -- Clinical cases, Jean Pascal 
       Machiels -- Updates from the European Head & Neck Society 
       (EHNS), Wojciech Golusinski (President of EHNS) Section 2:
       Primary disease Piero Nicolai -- Sensitivity and 
       specificity of extranodal extension in SCCHN: unlocking 
       the strongest prognostic factor in head and neck cancer, 
       Brian O'Sullivan -- From photon to proton: what's in it 
       for head and neck cancer patients?, Volker Budach -- 
       Lessons learned from RTOG 1016 and DE-ESCALaTE: what's 
       next?, Hisham Mehanna.-Treatment intensification in LA-
       SCCHN: what are the options and for who?, Jan Vermorken --
       Immune checkpoint inhibitors in the curative setting: 
       preclinical and clinical data, Jean-Pascal Machiels -- 
       Carcinoma of unknown primary: diagnostics and the 
       potential of transoral surgery, René Leemans -- Clinical 
       cases, Volker Budach -- Individualized therapy in 1-line R
       /M-SCCHN: what selection criteria should we use?, Petr 
       Szturz -- Patterns of response to immune oncology drugs: 
       how relevant are they in SCCHN?, Amanda Psyrri -- The role
       of radiotherapy in oligometastatic or oligoprogressive 
       disease in R/M-SCCHN, Daan Nevens -- Updates from the 
       EORTC Head and Neck Cancer Group (HNCG), Jean-Pascal 
       Machiels (Chair of EORTC-HNCG) -- Real world evidence in 
       head and neck cancer, Anil D'Cruz (UICC president -- 
       Pathology driven treatment of skull base tumors, Piero 
       Nicolai -- Modern day reconstruction of facial bones, Sat 
       Parmar -- Targeting molecular/minimal residual disease 
       using novel technologies and clinical trials design, 
       Lillian Siu -- New developments in surgery for malignant 
       salivary gland tumors, Jeroen Meulemans -- New systemic 
       therapies in salivary gland cancer, Ethan Argiris. 
       Exercise and nutrition interventions in head and neck 
       cancer, Paolo Bossi -- Telehealth intervention in head and
       neck cancer patients: a promise?, Irma Verdonck-de Leeuw. 
506 0  Open access.|5GW5XE 
520    This is an open access book. With a wealth of exciting 
       data emerging in this rapidly evolving field this book 
       will review the state-of-the-art knowledge with emphasis 
       on multidisciplinary decision and management of head and 
       neck cancer. The book provides significant detail on a 
       wide range of topics including: the role of new targets 
       for treatment, immunotherapy, resistance mechanisms, 
       standardizing molecular profiling programs, and new 
       methods to guide therapeutic approaches. In addition 
       different disease situations are addressed including 
       different treatment approaches in primary disease and in 
       recurrent and/or metastatic disease as well as new 
       developments in pathology, surgery and reconstruction 
       techniques, new systemic therapies in salivary gland 
       cancer, and supportive care and follow-up. All disciplines
       involved in the treatment of head & neck cancer are 
       covered with a focus on translation into daily practice. 
       The 8th-THNO is designed for medical oncologists, head and
       neck surgeons, radiation oncologists, otolaryngologists, 
       and other medical professionals involved in the treatment 
       of patients with head and neck cancer. 
588 0  Online resource; title from PDF title page (SpringerLink, 
       viewed April 6, 2023). 
590    Springer Nature|bSpringer Nature - SpringerLink eBooks - 
       Fully Open Access 
650  0 Head|xCancer|vCongresses. 
650  0 Neck|xCancer|vCongresses. 
650  7 Head|xCancer|2fast 
650  7 Neck|xCancer|2fast 
655  0 Electronic books. 
655  2 Congress 
655  7 proceedings (reports)|2aat 
655  7 Conference papers and proceedings|2fast 
655  7 Conference papers and proceedings.|2lcgft 
700 1  Vermorken, Jan B.,|eeditor. 
700 1  Budach, Volker,|eeditor. 
700 1  Leemans, C. René,|eeditor. 
700 1  Machiels, Jean-Pascal,|eeditor. 
700 1  Nicolai, P.|q(Piero),|d1954-|eeditor.|1https://id.oclc.org
       /worldcat/entity/E39PBJtGVTFDtRFDYYC46cQ6rq 
700 1  O'Sullivan, Brian,|d1952-|eeditor.|1https://id.oclc.org/
       worldcat/entity/E39PBJht99r7mdVxVfbBBcHt8C 
776 08 |cOriginal|z3031231740|z9783031231742|w(OCoLC)1351560296 
914    on1375084527 
994    92|bSTJ 
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