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Author Dunn, Ian S.

Title Searching for molecular solutions : empirical discovery and its future / Ian S. Dunn.

Publication Info. Hoboken, N.J. : John Wiley & Sons, [2010]
©2010

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Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Reference Material  PHARM QV 744 D923S 2010    In-Library Use Only
Description xix, 458 pages : illustrations ; 25 cm
Bibliography Includes bibliographical references and index.
Contents If it works, it works : pragmatic molecular discovery -- Empirical miracles : nature's precedents for empirical solutions -- Evolution's gift : natural somatic diversification and molecular design -- Evolution while you wait -- The blind protein maker -- The blind shaper of nucleic acids -- Evolving and creating recognition molecules -- Molecules small and large -- An empirical-rational loop forwards -- Exploring the limits.
Summary "Empirical methods of discovery, along with serendipitous and rational design approaches, have played an important role in human history. Searching for Molecular Solutions compares empirical discovery strategies for biologically useful molecules with serendipitous discovery and rational design, while also considering the strengths and limitations of empirical pathways to molecular discovery."--BOOK JACKET.
Subject Biochemistry -- Research.
Drugs -- Design.
Drug Discovery -- trends.
Chemistry, Pharmaceutical -- methods.
Combinatorial Chemistry Techniques -- methods.
Evolution, Molecular.
Molecular Structure.
Quantitative Structure-Activity Relationship.
ISBN 9780470146828 cloth
0470146826 cloth
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