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Book Cover

Title Handbook of drug screening / edited by Ramakrishna Seethala, Litao Zhang.

Publication Info. New York : Informa Healthcare, [2009]


Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Pharmacy Library  PHARM QV 771 H236 2009    In-Library Use Only
Edition Second edition.
Description xiii, 489 pages : illustrations ; 24 cm.
Series Drugs and the pharmaceutical sciences ; 196
Drugs and the pharmaceutical sciences ; v. 196.
Bibliography Includes bibliographical references and index.
Contents Key factors for successful high-throughput screening / John G. Houston -- Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston -- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy ... [et al.] -- Signal detection platforms for screening in drug discovery / Ramakrishna Seethala -- Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang -- Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic --
Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang -- Emerging novel high-throughput screening technologies for cell-based assays / ILona Kariv ... [et al.] -- In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop -- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel -- Protein kinases and phosphatases / Pirthipal Singh -- MicroRNA strategies in drug discovery / Wishva B. Herath -- Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli --
Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan -- High-content screening with a special emphasis on cytotoxicity and cell health measurements Ralph J. Garippa and Ann F. Hoffman -- Effective application of drug metabolism and pharmacokinetics in drug discovery Sharon Diamond and Swanny Yeleswaram -- Compound management for drug discovery : an overview Moneesh Chatterjee and Martyn N. Banks -- Practical approach to quantitative high throughput screening Wei Zheng, Ke Liu, and James Inglese -- Enabling the large-scale analysis of quantitative high-throughput screening data Noel T. Southall ... [et al.] -- Application of nanobiotechnologies for drug discovery / K.K. Jain.
Subject Drug development -- Handbooks, manuals, etc.
Drugs -- Testing -- Handbooks, manuals, etc.
Drug Evaluation, Preclinical -- methods.
Added Author Seethala, Ramakrishna, 1947-
Zhang, Litao.
Other Form: Online version: Handbook of drug screening. 2nd ed. New York : Informa Healthcare, c2009 (OCoLC)777256236
ISBN 9781420061680 hardcover alkaline paper
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