LEADER 00000cam 2200517Ki 4500 001 ocn743217483 003 OCoLC 005 20160518075904.2 006 m o d 007 cr cnu---unuuu 008 110728s2010 njua ob 001 0 eng d 019 741454282|a816846104 020 9789814280907|q(electronic bk.) 020 9814280909|q(electronic bk.) 020 9789814280914|q(electronic bk.) 020 9814280917|q(electronic bk.) 020 9781613447796|q(electronic bk.) 020 1613447795|q(electronic bk.) 035 (OCoLC)743217483|z(OCoLC)741454282|z(OCoLC)816846104 040 N$T|beng|epn|erda|cN$T|dYDXCP|dOCLCQ|dOCLCO|dKNOVL|dOCLCQ |dZCU|dOCLCQ|dKNOVL|dOCLCF|dNLGGC|dKNOVL|dIDEBK|dOCLCQ |dOCLCA 049 GTKE 050 4 RB155.8|b.G85 2010eb 060 4 2010 J-726 060 4 QZ 52 082 04 615.895|223 245 02 A guide to human gene therapy /|ceditors Roland W. Herzog, Sergei Zolotukhin. 264 1 New Jersey ;|aLondon :|bWorld Scientific,|c[2010] 264 4 |c©2010 300 1 online resource (xxvi, 388 pages) :|billustrations (some color) 336 text|btxt|2rdacontent 337 computer|bc|2rdamedia 338 online resource|bcr|2rdacarrier 504 Includes bibliographical references and index. 520 Ever since the birth of molecular biology " the tantalizing possibility of treating disease at its genetic roots has become increasingly feasible. Gene therapy â" though still in its infancy â" remains one of the hottest areas of research in medicine. Its approach utilizes a gene transfer vehicle (""vector"") to deliver therapeutic DNA or RNA to cells of the body in order to rectify the defect that is causing the disease. Successful therapies have been reported in humans in recent years such as cures in boys with severe immune deficiencies. Moreover" gene therapy strategies are being adapted in numerous biomedical laboratories to obtain novel treatments for a variety of diseases and to study basic biological aspects of disease. Correction of disease in animal studies is steadily gaining ground highlighting the immense potential of gene therapy in the medical profession. This book will cover topics that are at the forefront of biomedical research such as RNA interference viral and non-viral gene transfer systems treatment of hematological diseases and disorders of the central nervous system. Leading experts on the respective vector or disease will contribute the individual chapters and explain cutting-edge technologies. It also gives a broad overview of the most important gene transfer vectors and most extensively studied target diseases. This comprehensive guide is therefore a must- read for anyone in the biotechnology biomedical or medical industries seeking to further their knowledge in the area of human gene therapy. 588 0 Print version record. 650 0 Gene therapy. 650 2 Genetic Therapy. 650 7 PSYCHOLOGY|xPsychotherapy|xGeneral.|2bisacsh 650 7 Gene therapy.|2fast|0(OCoLC)fst00939638 700 1 Herzog, Roland W.,|d1970- 700 1 Zolotukhin, Sergei. 776 08 |iPrint version:|tGuide to human gene therapy.|dNew Jersey ; London : World Scientific, ©2010|z9789814280907 |w(OCoLC)660502539 914 ocn743217483 994 93|bGTK
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