| Edition |
7th ed. |
| Description |
1 online resource (xii, 490 pages) : illustrations |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Definitions and glossary -- The LADMER system: liberation, absorption, distribution, metabolism, elimination, and response -- Organs, tissues, cells, and organelles -- Cell membranes -- Drug-receptor interactions -- Absorption/transport mechanisms -- pKa and degree of ionization -- Lipid/water partition coefficient -- Physicochemical factors altering biological performance of drugs -- Biopharmaceutical data of the gastrointestinal tract -- Fluid compartments and circulatory system -- Binding of drugs to biological material -- Drug biotransformation -- Compartment models -- Determination of rate constants -- Volume of distribution and distribution coefficient -- Excretion and clearance of drugs -- Urinary and biliary recycling -- Cumulative urinary excretion -- Area under the blood level-time curve -- Pharmacokinetics of single dose administration -- Pharmacokinetics of multiple dosing -- Compartment model independent analysis -- Pediatric pharmacokinetics -- Drug dosage in elderly patients -- Drug dosage in obese patients -- Drug disposition in pregnancy -- Dosage regimen design -- Drug monitoring and dosage adjustment -- Physiological and pathological factors influencing drug response -- First dosage size in man -- Forensic pharmacokinetics -- Nonlinear pharmacokinetics -- Curve fitting -- Correlation of clinical response with drug disposition -- Bioavailability and bioequivalence -- Body surface areas -- Extracorporeal methods of drug removal -- Pharmacogenetics and pharmacogenomics. |
| Note |
Description based on print version record. |
| Local Note |
STJOEBOOK |
| Note |
GMD: electronic resource. |
| Subject |
Pharmacokinetics -- Handbooks, manuals, etc.
|
|
Clinical pharmacology -- Handbooks, manuals, etc.
|
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Pharmacokinetics -- Handbooks.
|
| Added Author |
Kearns, Gregory L.
|
|
American Pharmaceutical Association.
|
| In: |
PharmacyLibrary (OCoLC)676775441 |
| Other Form: |
Ritschel, W. A. (Wolfgang A.). Handbook of basic pharmacokinetics-- including clinical applications. 7th ed. Washington, D.C. : American Pharmacists Association, c2009 9781582121260 (DLC) 2009020352 (OCoLC)313655800 |
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