| Edition |
Sixth edition. |
| Description |
xviii, 811 pages : illustrations ; 25 cm |
| Bibliography |
Includes bibliographical references and index. |
| Contents |
Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model: intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple-dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo : bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics to clinical situations -- Dosage adjustment in renal and hepatic disease -- Physiologic pharmacokinetic models, mean residence time, and statistical moment theory. |
| Subject |
Biopharmaceutics.
|
|
Pharmacokinetics.
|
|
Biopharmaceutics.
|
|
Models, Chemical.
|
|
Pharmacokinetics.
|
| Added Author |
Yu, Andrew B. C., 1945-
|
|
Wu-Pong, Susanna.
|
| Note |
Applied biopharmaceutics and pharmacokinetics |
| ISBN |
9780071603935 hardcover alkaline paper |
|
007160393X hardcover alkaline paper |
|
