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Title Textbook of receptor pharmacology / edited by John C. Foreman, Torben Johansen, Alasdair J. Gibb.

Publication Info. Boca Raton, FL : CRC Press, [2011]


Location Call No. Status
 University of Saint Joseph: Pope Pius XII Library - Reference Material  PHARM QV 38 T355 2011    In-Library Use Only
Edition Third edition.
Description xi, 291 pages, 8 unnumbered pages of plates : illustrations (some color) ; 27 cm
Bibliography Includes bibliographical references and index.
Summary "Providing an introduction to the study of drug receptors, the Textbook of receptor pharmacology discusses quantitative descriptions of functional studies with agonists and antagonists; quantitative descriptions of ligands binding to receptors; the molecular structures of drug receptors; and the elements that transport the signal from the activated receptor to the intracellular compartment. This third edition features results from recent research on how the structure of receptors determines the interaction between the receptor and the signal transducer. This edition also offers new information on ligand binding receptor studies that use newly developed techniques"--Provided by publisher.
Contents Classical Approaches to the Study of Drug-Receptor Interactions / Donald H. Jenkinson -- Structure and Function 7-TM G-Protein Coupled Receptors / Alasdair J. Gibb -- The Structure of Ligand-Gated Ion Channels / Jan Egebjerg -- Molecular Structure of Receptor Tyrosine Kinases / IJsbrand Kramer and Michel Laguerre -- Direct Measurement of Drug Binding to Receptors / Dennis G. Haylett -- Receptors Linked to Ion Channels: Mechanisms of Activation and Block / Alasdair J. Gibb -- G-Proteins / David A. Brown -- Signal Transduction through Protein Tyrosine Kinases / IJsbrand Kramer and Elisabeth Genot -- Receptors as Pharmaceutical Targets / James W. Black.
Subject Drug receptors.
Receptors, Drug -- agonists.
Receptors, Drug -- antagonists & inhibitors.
Radioligand Assay -- methods.
Receptors, Drug -- physiology.
Signal Transduction -- physiology.
Added Author Foreman, John C.
Johansen, Torben.
Gibb, Alasdair J.
ISBN 9781420052541 hardcover alkaline paper
1420052543 hardcover alkaline paper
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