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Title Genome editing in neurosciences / Rudolf Jaenisch, Feng Zhang, Fred Gage, editors.

Publication Info. Cham, Switzerland : Springer, 2017.

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 University of Saint Joseph: Pope Pius XII Library - Internet  WORLD WIDE WEB E-BOOK Springer    Downloadable
Please click here to access this Springer resource
 University of Saint Joseph: Pope Pius XII Library - Internet  WORLD WIDE WEB E-BOOK Springer    Downloadable
Please click here to access this Springer resource
Description 1 online resource (xi, 123 pages) : color illustrations.
text file PDF rda
Series Research and perspectives in neurosciences, 0945-6082
Research and perspectives in neurosciences. 0945-6082
Access Open access. GW5XE
Note Online resource; title from PDF title page (SpringerLink, viewed September 25, 2017).
Contents Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington's Disease -- Therapeutic gene editing in muscles and muscle stem cells.
Summary This book is open access under a CC BY 4.0 license. Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque M├ędecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.
Local Note SpringerLink Springer Nature Open Access eBooks
Subject Neurogenetics.
Genetic engineering.
RNA editing.
Gene Editing.
Neurosciences.
Genetic engineering. (OCoLC)fst00940027
Neurogenetics. (OCoLC)fst01036353
RNA editing. (OCoLC)fst01086255
Added Author Jaenisch, Rudolf, editor.
Zhang, Feng, 1982- editor.
Gage, F. (Fred), 1950- editor.
Other Form: Print version: Genome editing in neurosciences. Cham, Switzerland : Springer, 2017 9783319601915 3319601911 (OCoLC)987282339
ISBN 9783319601922 (electronic book)
331960192X (electronic book)
9783319601915 (print)
Standard No. 10.1007/978-3-319-60192-2 doi
ISBN 3319601911
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